Current postings
Postdoctoral Postings
Postdoctoral Fellow (1 of 2): Examining the contribution of NK cell TGFb signaling to pulmonary vascular development and the pathobiology of pulmonary hypertension
Summary: Applications are solicited for a Postdoctoral fellow position focusing on understanding the mechanisms by which natural killer (NK) cells and other innate lymphocyte populations influence pulmonary vascular development in early life, as well as pathological cardiopulmonary remodelling in diseases like pulmonary hypertension. More specifically, we are looking for a candidate who is interested in joining a team with broad and complementary expertise (e.g., developmental, molecular and cellular biology, small animal physiology, and bioinformatics) whose major goal is to dissect the mechanisms by which NK cells influence blood vessel patterning in the lung using state-of-the art in vivo models and ex vivo cell culture assays. This project will be particularly focused on the contribution of NK cell TGFb signalling to these processes. To this end, the candidate will be exposed to a multidisciplinary training program comprising a variety of well-established molecular and cell biology methods, small animal (genetically modified mice and rats) disease models, and newly developed systems biology (single nuclear and spatial transcriptomics) and bioinformatic approaches.
Qualifications: Interested candidates must hold a Ph.D. whereby the advantage will be given to those candidates with the strongest expertise in immune and cardiovascular methods (with a particular emphasis on ex vivo immune cell functional assays). Experience with breeding and working with complex genetic mouse models, such as tissue-specific inducible knockouts, will also be considered a strength. Previous authorship of high-quality publications in these or related areas will be expected. Evidence of interpersonal skills and the ability to work collaboratively in a team will be sought.
Job Details: The position will be held in the Ormiston Lab at Queen’s University. The contract will have a one year probationary period and may be extended for up to five years. The salary will be competitive and commensurate with experience. Applicants should submit, in electronic form: curriculum vitae, names and contact information of three references and a signed letter of interest describing relevant experience and qualifications to Dr. Mark Ormiston (mark.ormiston@queensu.ca).
Equal Opportunity Employer Statement: All qualified candidates are encouraged to apply. Queen’s University is committed to diversity and equity in employment. It welcomes applications from indigenous peoples, visible minorities, ethnic minorities, persons with disabilities, women, persons of minority sexual orientations and gender identities and others who may contribute to further diversification.
Only the selected candidates will be contacted for an interview.
Postdoctoral Fellow (2 of 2): Examining the contribution of BMPR2 loss to endothelial dysfunction in PAH
Summary: Applications are solicited for a Postdoctoral fellow position focusing on understanding the mechanisms by which mutations in BMPR2 and dysregulated bone morphogenetic protein (BMP) signaling influence endothelial function, angiogenesis and the pathogenesis of pulmonary arterial hypertension (PAH). More specifically, we are looking for a candidate who is interested in joining a team with broad and complementary expertise (e.g. molecular and cellular biology, small animal physiology, and bioinformatics) whose major goal is to dissect the mechanisms by which BMP signaling regulates endothelial proliferation and apoptosis at the level of transcriptional and translational control. To this end, the candidate will be exposed to a multidisciplinary training program comprising a variety of well-established molecular and cell biology methods, small animal disease models, and bioinformatic approaches.
Qualifications: Interested candidates must hold a Ph.D. whereby the advantage will be given to those candidates with the strongest expertise in cell and molecular biology (with a particular emphasis on translational regulation, intracellular trafficking, the endothelial stress response, and a knowledge of techniques for the identification and validation of protein-protein and protein-RNA interactions). Experience with complex bioinformatic analysis methods will also be considered a strength. Previous authorship of high-quality publications in these or related areas will be expected. Evidence of interpersonal skills and the ability to work collaboratively in a team will be sought.
Job Details: The position will be held in the Ormiston Lab at Queen’s University. The contract will have a one year probationary period and may be extended for up to five years. The salary will be competitive and commensurate with experience. Applicants should submit, in electronic form: curriculum vitae, names and contact information of three references and a signed letter of interest describing relevant experience and qualifications to Dr. Mark Ormiston (mark.ormiston@queensu.ca).
Equal Opportunity Employer Statement: All qualified candidates are encouraged to apply. Queen’s University is committed to diversity and equity in employment. It welcomes applications from indigenous peoples, visible minorities, ethnic minorities, persons with disabilities, women, persons of minority sexual orientations and gender identities and others who may contribute to further diversification.
Only the selected candidates will be contacted for an interview.